Tuesday, January 17, 2017

HEAVIER THAN...



 ....a pound of bacon.
They are just 
the healthiest little pups
and growing like bad weeds!!

We can now 
share with you
where two of the puppies
are going to live
and their new names!!


 Let us introduce
Rocky Creek's Luke Skywalker MacCelti
formerly known as
Hoss.

He will be going to live
in the big state of Texas.

We probably should tell you
how he got his original name.
When Celti was in labor,
there was a puppy who was
blocking the exit.
That puppy was named
in memory of Dan Blocker
so we called him
Hoss.


 So far Snazzi
doesn't have a home
but we feel certain
that she will 
by the end of the week.


Mom is a bit envious
of Jazzi's new name!!
She is
Rocky Creek's Ruby Red MacCelti.

Ruby will be going 
to live in Michigan.


Check out these 
"kankles". 
So many wrinkles
on an inch long leg!!

It makes us giggle
every time we see them!!

XOXO,
Piper, Celti, Bonnie, Ruben,
Ivy
and
The Love Bugs

Thursday, January 12, 2017

GROWING LIKE LITTLE PUPPIES SHOULD


Every time we look
at the puppies,
we are amazed 
at how they are
growing and thriving. 

Mom laughs
about the fact
that they all 
have fat wrinkles
on their little
one inch long legs.


 This is Hoss.

 This is Snazzi.

 This is Jazzi.

And look at Jazzi here!!
We think she'll be 
over a pound by 
this evening's weighing.

XOXO,
Piper, Celti, Bonnie, Ruben
Ivy
and
The "Love Bugs"

Tuesday, January 10, 2017

WE KNOW...WE ARE THE LAZIEST!!

When you've got new puppies
in the house,
and your Sissy is visiting
from California
and it's snowing,
it easy to just
wile away the days
doing nothing
and rocking puppies.

Even Celti and the
puppies are doing 
a lot of relaxing.

Can you tell them apart?

Tomorrow,
we'll be back blogging
and doing our daily
cuteness overload.

See you then. 

XOXO,
Piper, Celti, Bonnie Ruben,
Ivy
and
The Love-Bugs 

Thursday, January 5, 2017

THREE LITTLE LOVE-BUGS


On Tuesday night,
Mom said she was a "pop-tart" -
jumping up and down
out of bed 
every time Celti moved.


Yesterday,
Wednesday,
Celti kept looking 
at Mom like she
really needed some help.

Then she started 
into hard labor
and 
nothing was happening.

Mom got scared
and called our Vet.

Our friend, Wava,
who works in the front office
relayed Mom's worries
to a nice lady dogtor
that we had never met before.

She said that if nothing happened
by 1:30 pm
that we needed to 
bring Celti in.

Since our Sissy is visiting,
Mom enlisted her to drive
them to the Vet.

Mom took her 
medical bag with her
just in case
a puppy was born in the car.

When they got there,
Mom told the dogtor
what was happening 
and she suggested
that Celti have a 
c-section.

Mom quickly agreed!!

Within the hour,
we got the news 
that there are three new
Rocky Creek Scotties 
that will grace the world.


A little boy
and a little girl.



And Jazzi - 
another little girl!!



Celti and the puppies
are all doing great!!

We are anxious to
get to the waiting list
to see where 
they will go to live!!
There are some people 
who have been waiting 
for several years!!

Our Vet
made us promise
that they wouldn't be
going to Australia!!
he-he-he!

XOXO,
Piper, Celti, Bonnie, Ruben<
Ivy
and 
The Three Little Love-Bugs


Monday, January 2, 2017

GUESS WHAT WE'RE WAITING FOR....


 In December,
Ms. Sydney
from
sent us some 
special food
so we'd be ready 
for today
or 
tomorrow.

 It's a Superblend
that will supercharge
our regular food
but she sent it 
especially for Celti!!


Mom has a lot of 
funny smelling instruments 
laid out on her little table.



Celti saw her dogtor
this morning 
and he took a photograph
of her insides.

Soon we hope to
hear the "pitter-patter".

XOXO,
Piper, Celti, Bonnie, Ruben
and 
Ivy

Friday, October 21, 2016

THE RAINBOW BRIDGE

Several years back,
when Carrleigh's puppies were due,
Nurse Lilly
put out the call
for help.

Nurse Lilly
had worked her little toes
"to the bone"
waiting on Carrleigh 
"hand and paw".


All at once
a private plane 
circled our pasture
and landed.

Out stepped
these three beauties,

Of course Lacie
didn't go anywhere
without her pawsonal blender!!


Those were the days!!  
Fun with blogging!!

Today is a sad day
for us at
Rocky Creek Farm.

We have just found out that
Nurse Agatha
has joined
Nurse Lilly
across the Rainbow Bridge.

We are grieving
with her family. 

XOXO,
Piper, Celti, Bonnie
and 
Ivy

Friday, September 30, 2016

CUSHINGS STUDY AT VIRGINIA TECH/MARYLAND





As you all know, Cushings is a prevalent disease among Scottish Terriers.  Although none of us have ever been diagnosed with it, we are aware that it can happen at any time.  It is a manageable disease and once diagnosed a dog can live a happy and full life with a few minor adjustments. 

Virginia-Maryland College of Veterinary Medicine invited all Scottish Terriers in the area to participate in the study.  Below you will find an update.

 Dear Scottie supporters,

Thank you to those veterinarians and owners who participated in the Virginia-Maryland College of Veterinary Medicine’s study of Atypical Cushing’s in Scottish terriers. We wanted to provide an update on our research findings for those who may be interested in learning more.

Atypical Cushing’s in Scotties

Cushing’s disease is a chronic debilitating disorder in dogs. Scotties have an unusually high incidence of Cushing’s. It can contribute to the development of diabetes, obesity, immune system problems, inappropriate urination, and other negative health outcomes. In normal dogs, the pituitary gland and adrenal glands produce hormones necessary for the function of many systems in the body. If something goes wrong in these glands and certain hormones are overproduced, then Cushing’s can develop. These abnormalities are often detected by observing clinical signs and when routine blood work shows elevations in a liver protein called ALP.

Our Earlier Findings

Preliminary data indicate that in Scottish Terriers, the cause of atypical Cushing’s appears to be due to excessive amounts of noncortisol steroids, which is an atypical form of the disease. These findings prompted the group at the vet school here to speculate that there might be a unique underlying cause for atypical Cushing’s in this breed. The study you participated in was designed to test those theories.

Our preliminary research, which has been ongoing for several years, had already figured out a few things:

· In the most common form of Cushing’s, excessive amounts of a single hormone from the pituitary gland signals the adrenal gland to overproduce cortisol. However, in Scotties excessive amounts of sex hormones, not cortisol, are observed.

· This increased production of adrenal sex hormones is not due to excessive amounts of a variety of pituitary signaling hormones.

· These elevated concentrations of sex hormones are the cause for the increased ALP values commonly seen in these dogs.

· There is no indication of adrenal cancer as a cause for this increased production of sex hormones.

· The magnitude of ALP elevations increases over time, but pituitary and adrenal regulation do not change.

The Virginia-Maryland college team identified 3 candidate genes in a very small pool of patients which are uniquely expressed in Scotties with atypical disease compared to normal Scotties and other breeds with Cushing’s disease, and undertook the study you participated in to understand how these genes might influence the development of atypical Cushing’s.

The Newest Study

The latest study you participated in found that there was indeed a genomic variation in Scottish terriers that was associated with increased serum ALP activity. The variation was located on the same chromosome as a gene responsible for inactivation of sex steroids. Genes can be active (expressed) or inactive (not expressed). If genes are overexpressed, their effect can increase. If they are under expressed, their effect is reduced. In Scotties, the sex steroid inactivation gene was under expressed in comparison to other breeds with Cushing’s disease (pituitary dependent hyperadrenocorticism). We suggest the gene variation seen in Scotties may be linked with “turning off” this sex steroid inactivation gene, leading to increased concentrations of sex steroids. We believe the higher concentrations of these sex steroids may explain commonly observed liver and ALP changes seen in Scottish terriers.

Questions?

The results will be published in academic journals, shared with the AKC’s Canine Health Foundation, and published on the AVMA’s clinical research website. We hope that better understanding of the mechanisms of this disease in Scotties can lead to better treatments for affected dogs. 

If you have any questions about this research, please don’t hesitate to get in touch.

Mindy Quigley

Clinical Trials Coordinator

Veterinary Clinical Research Office

Virginia Tech

Virginia-Maryland College of Veterinary Medicine

205 Duck Pond Drive

Blacksburg, VA 24061

Office Phone: 540-231-1363

Web: http://www.vetmed.vt.edu/clinical-trials/ 

Working Hours: T, W, TH (8:30am-5pm)
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